CJC-1295 + Ipamorelin Blend
The CJC-1295 + Ipamorelin Blend is a synergistic combo that strongly stimulates natural Growth Hormone (GH) release. CJC-1295 (long-acting) provides consistent GH/IGF-1 elevation, while Ipamorelin (pulse-driven) ensures peak GH release. It is key for research into muscle growth, anti-aging, fat loss, and recovery.
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The CJC-1295 + Ipamorelin Blend combines two powerful peptides that stimulate the body’s natural growth hormone (GH) release. CJC-1295 with DAC provides long-acting stimulation of GH by binding to albumin, allowing consistent elevation of GH and IGF-1. Ipamorelin complements this by mimicking ghrelin and targeting the GH secretagogue receptor for pulse-driven GH release. Together, this synergistic blend is widely researched for muscle growth, anti-aging, fat metabolism, and recovery enhancement.
– Form: Lyophilized peptide blend
– Purity: >99%
– Origin: Manufactured and tested in the USA
– Certifications: Certificate of Analysis (COA) included
This blend works through dual pathways:
– CJC-1295 stimulates GHRH receptors and extends GH pulse via DAC binding
– Ipamorelin activates ghrelin receptors, enhancing natural GH bursts
– Combined, they increase GH and IGF-1 levels without elevating cortisol or prolactin
– Promotes lipolysis, muscle recovery, and cellular regeneration
– Lean muscle mass development
– Fat metabolism and lipolysis studies
– Injury recovery and tissue repair
– Anti-aging and regenerative research
– Hormonal optimization without desensitization
– Synergistic effect on GH stimulation
– Minimal impact on cortisol/prolactin levels
– Stable, long-acting performance from CJC-1295 DAC
– Rapid GH bursts from Ipamorelin
Each vial is:
– Produced in a GMP-compliant U.S. facility
– Supplied with a Certificate of Analysis (COA)
– Verified via HPLC and mass spectrometry
– Shipped securely from the USA
– Contents: 5mg blend (2.5mg CJC-1295 DAC + 2.5mg Ipamorelin)
– Appearance: White/off-white lyophilized powder
– Solubility: Sterile bacteriostatic water recommended
– Storage: Store lyophilized powder at -20°C; stable for 30 days post-reconstitution if refrigerated
*For laboratory research use only. Not intended for human or veterinary use.*
– Sold strictly for research purposes
– Not for human consumption or diagnostic use
– Researchers must follow all applicable laws and institutional review protocols
This popular research peptide combination includes two synergistic compounds: CJC-1295, a growth hormone-releasing hormone (GHRH) analog, and Ipamorelin, a selective growth hormone secretagogue (GHS). Together, they are studied for their ability to enhance natural growth hormone release, support tissue regeneration, and promote lean body composition in laboratory settings.
CJC-1295 stimulates the pituitary gland by mimicking GHRH, resulting in prolonged growth hormone release. Ipamorelin works by targeting ghrelin receptors to amplify GH pulses without significantly affecting cortisol or prolactin levels. Their complementary mechanisms create a stable and amplified growth hormone profile useful for metabolic and recovery-focused research.
Shop Peptides Direct offers this blend as a lyophilized powder in sterile, sealed vials. It is pre-mixed in precise ratios to ensure consistency and ease of use in research environments. As with all our peptides, it’s lab-tested and U.S.-manufactured.
No. This product is strictly for research use only. It is not intended for human or veterinary administration, diagnosis, or treatment purposes.
Store the lyophilized vial at -20°C in a cool, dry, and light-protected environment. Once reconstituted, refrigerate the solution between 2–8°C and use it promptly based on research stability guidelines.
Every batch is tested and confirmed to be ≥98% pure using HPLC and Mass Spectrometry. A full Certificate of Analysis (COA) accompanies every order, guaranteeing quality and consistency for your research.
Yes. While the product remains stable during shipping in standard packaging, cold-chain shipping is available upon request for sensitive projects or bulk orders.
Researchers often pair this blend with other hormone analogs or metabolic regulators for advanced studies. All such combinations must comply with approved lab protocols and safety guidelines.
Visit our Lab Test Results page, select ‘CJC-1295 + Ipamorelin Blend’ from the dropdown menu, and provide your email address. We’ll send you the batch-specific COA for full transparency.
Our CJC-1295 + Ipamorelin Blend is produced in the USA, lab-verified for ≥98% purity, and shipped fast with care. We also offer a Price Match Guarantee—if you find equivalent quality elsewhere for less, we’ll match it. With every order, you receive trusted documentation and the support of a dedicated team focused on your research success.
CJC-1295 NO DAC + Ipamorelin (10 mg Blend) Dosage Protocol
Quickstart Highlights
This blend combines CJC-1295 (no DAC), a modified growth hormone-releasing hormone (GHRH) analog, with Ipamorelin, a selective growth hormone secretagogue (GHS)[1][2]. CJC-1295 (no DAC) produces sustained, dose-dependent GH and IGF-1 increases[1], while Ipamorelin selectively stimulates GH release without raising ACTH or cortisol[3]. This educational protocol presents a once-daily subcutaneous approach using a practical dilution for clear insulin-syringe measurements.
- Reconstitute: Add 3.0 mL bacteriostatic water → ~3.33 mg/mL total concentration (1.67 mg/mL each peptide).
- Typical daily range: 100–300 mcg of each peptide once daily (gradual titration).
- Easy measuring: At 3.33 mg/mL total, 1 unit = 0.01 mL ≈ 33.3 mcg of each peptide on a U-100 insulin syringe.
- Storage: Lyophilized: freeze at −20 °C (−4 °F); after reconstitution, refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
Dosing & Reconstitution Guide
Educational guide for reconstitution and daily dosing
Standard / Gradual Approach (3 mL = ~3.33 mg/mL total)
| Week | Daily Dose (mcg each) | Units (per injection) (mL) |
|---|---|---|
| Weeks 1–2 | 100 mcg each | 3 units (0.03 mL) |
| Weeks 3–4 | 150 mcg each | 4.5 units (0.045 mL) |
| Weeks 5–6 | 200 mcg each | 6 units (0.06 mL) |
| Weeks 7–12 | 250–300 mcg each | 7.5–9 units (0.075–0.09 mL) |
Frequency: Inject once daily subcutaneously, typically before bed or upon waking[4]. For ≤10-unit (≤0.10 mL) administrations, consider 30- or 50-unit insulin syringes for improved readability.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall; avoid foaming.
- Gently swirl/roll until dissolved (do not shake).
- Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.
Supplies Needed
Plan based on an 8–16 week daily protocol with gradual titration.
- Peptide Vials (CJC-1295 NO DAC + Ipamorelin, 10 mg blend each):
- 8 weeks ≈ 3 vials
- 12 weeks ≈ 4 vials
- 16 weeks ≈ 5 vials
- Insulin Syringes (U-100, 30- or 50-unit preferred for low volumes):
- Per week: 7 syringes (1/day)
- 8 weeks: 56 syringes
- 12 weeks: 84 syringes
- 16 weeks: 112 syringes
- Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.
- 8 weeks (3 vials): 9 mL → 1 × 10 mL bottle
- 12 weeks (4 vials): 12 mL → 2 × 10 mL bottles
- 16 weeks (5 vials): 15 mL → 2 × 10 mL bottles
- Alcohol Swabs: One for the vial stopper + one for the injection site each day.
- Per week: 14 swabs (2/day)
- 8 weeks: 112 swabs → recommend 2 × 100-count boxes
- 12 weeks: 168 swabs → recommend 2 × 100-count boxes
- 16 weeks: 224 swabs → recommend 3 × 100-count boxes
Protocol Overview
Concise summary of the once-daily regimen.
- Goal: Support pulsatile GH release through synergistic GHRH + GHS stimulation[4].
- Schedule: Daily subcutaneous injections for 8–12 weeks (extend to 16 weeks if desired).
- Dose Range: 100–300 mcg of each peptide daily with gradual titration.
- Reconstitution: 3.0 mL per 10 mg vial (~3.33 mg/mL total) for accurate unit measurements.
- Storage: Lyophilized frozen; reconstituted refrigerated; avoid repeated freeze–thaw.
Dosing Protocol
Suggested daily titration approach.
- Start: 100 mcg each peptide daily; increase by ~50 mcg every 1–2 weeks as tolerated.
- Target: 200–300 mcg each peptide daily by Weeks 5–12.
- Frequency: Once per day (subcutaneous).
- Cycle Length: 8–12 weeks; optional extension to 16 weeks.
- Timing: Typically before bed or upon waking; rotate injection sites.
Storage Instructions
Proper storage preserves peptide quality.
- Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions; minimize moisture exposure.
- Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); use within ~28 days; avoid freeze–thaw.
- Allow vials to reach room temperature before opening to reduce condensation uptake.
Important Notes
Practical considerations for consistency and safety.
- Use new sterile insulin syringes; dispose in a sharps container.
- Rotate injection sites (abdomen, thighs, upper arms) to reduce local irritation.
- Inject slowly; wait a few seconds before withdrawing the needle.
- Document daily dose and site rotation to maintain consistency.
- For doses under 10 units, use 30- or 50-unit syringes for better precision.
How This Works
CJC-1295 (no DAC) is a modified GHRH analog (tetrasubstituted 29-amino acid peptide) that stimulates pulsatile GH release from the pituitary[1]. Human studies demonstrate sustained, dose-dependent increases in both GH and IGF-1 with subcutaneous administration[1]. Ipamorelin is a pentapeptide GH secretagogue with a half-life of approximately 1.5–2.5 hours[5] that elicits a rapid GH pulse peaking around 40 minutes post-dose[6]. Importantly, Ipamorelin selectively increases GH without affecting ACTH, cortisol, or prolactin levels[3]. When combined, these peptides may produce synergistic GH release by acting on complementary receptor pathways[4].
Potential Benefits & Side Effects
Observations from preclinical and clinical literature.
- Supports sustained GH and IGF-1 elevation through pulsatile release patterns[1][2].
- Ipamorelin demonstrates selective GH release without cortisol or ACTH elevation[3].
- Once-daily dosing of CJC-1295 (no DAC) has been shown to normalize growth in animal models[2].
- Generally well tolerated; possible transient effects may include flushing, headache, or injection-site reactions.
- Some individuals report increased appetite, water retention, or tingling sensations.
Lifestyle Factors
Complementary strategies for best outcomes.
- Pair with a balanced, protein-forward diet tailored to energy needs.
- Combine resistance training and aerobic activity to reinforce metabolic adaptations.
- Prioritize sleep quality, as GH is predominantly released during deep sleep.
- Manage stress to support optimal hormonal balance and recovery.
Injection Technique
General subcutaneous guidance from clinical best-practice resources[7].
- Clean the vial stopper and skin with alcohol; allow to dry.
- Pinch a skinfold; insert the needle at 45–90° into subcutaneous tissue[7][8].
- Do not aspirate for subcutaneous injections; inject slowly and steadily[7].
- Rotate sites systematically (abdomen, thighs, upper arms) to avoid lipohypertrophy[9].
Recommended Source
We recommend Shop Peptides Direct for high-purity CJC-1295 NO DAC + Ipamorelin (10 mg Blend).
Why Shop Peptides Direct?
- High-purity, third-party-tested lots with batch COAs.
- Consistent, ISO-aligned handling and documentation.
- Reliable fulfillment to maintain cold-chain integrity.
Important Note
This content is intended for therapeutic educational purposes only and does not constitute medical advice, diagnosis, or treatment.
References
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PubMed — Prolonged stimulation of GH and IGF-1 secretion by CJC-1295 in healthy adults
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PubMed — Once-daily CJC-1295 normalizes growth in GHRH knockout mouse
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PubMed — Ipamorelin, the first selective growth hormone secretagogue
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PMC — Beyond the androgen receptor: GH secretagogues in body composition management
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PubMed — Pharmacokinetic-pharmacodynamic modeling of ipamorelin in human volunteers
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PubMed — Ipamorelin GH pulse kinetics and timing studies
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CDC — Vaccine administration: subcutaneous route (angle/site; no aspiration)
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CDC (Subcut Injection PDF) — Technique diagram and site guidance for subcutaneous injections
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NCBI Bookshelf — Best practices for injection (asepsis, preparation, and administration)
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Subcutaneous Drug Injection Review (PMC) — Pharmacologic considerations of the subcutaneous route
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Frontiers in Endocrinology — Growth hormone secretagogues: history and clinical applications
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Endocrine Reviews — Ghrelin and growth hormone secretagogues: physiology and applications
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